Insights into the biocompatibility of human gingival fibroblasts cultured on a hydroxyapatite-coated new Ti-Nb Alloy. New perspectives for dentistry?

The increasing demand for biomaterials with enhanced performance in medical implants has led to significant advancements in the development of titanium alloys, particularly titanium-niobium (Ti-Nb) alloys. These materials are favored for their exceptional mechanical properties, corrosion resistance, and biocompatibility, rendering them excellent candidates for a variety of orthopedic and dental implants. However, further improvements in their cytocompatibility are vital to promote better integration with the surrounding tissues. One approach to accomplish this is through surface modification, such as coating the Ti-Nb implants with hydroxyapatite (HAp), a bioceramic material known for its similarity to bone mineral and its positive impact on cell attachment and osseointegration. This experimental study aims to compare the cytocompatibility of Ti-Nb implants with and without a hydroxyapatite coating, assessing their potential for enhancing tissue integration and overall implant performance.